Designed to Support Your Naturally Thrives

We focus on perimenopause because it's the most misunderstood and under-served phase of women's health. The decade between 35-55 isn't "early menopause"—it's a distinct biological event where estrogen, progesterone, and cortisol collapse simultaneously, creating a perfect storm of metabolic, structural, and emotional disruption...
  • Research-Driven (Clinical doses based on published studies, not marketing trends)
  • Women-Founded (Built by women who understand the crisis because we've lived it)
  • Transparent (Every ingredient, dose, and mechanism clearly explained)
  • Results-Focused (90-day guarantee because we believe in what we've formulated)
Learn More

Four Formulas. One Mission.

Support what estrogen loss took away

Metabolize

Women's Cellular Metabolism Reset

Common Struggles:

  • Stubborn belly fat despite eating less
  • 2 PM brain fog and energy crashes
  • Sugar cravings that feel overwhelming
  • Concerns about blood sugar health
  • What Users Report:
  • Week 1-2: Cravings quiet. Energy feels more stable.
  • Week 3-4: Clothes fit better. Mental clarity improves.
  • Week 8-12: Sustained metabolic support.
Get Metabolize

PuraBiome

Support Healthy Intimate Balance

Common Struggles:

  • Recurring BV and UTIs every 2-3 months
  • Odor concerns that affect confidence
  • Bloating that forces wardrobe changes
  • Infection → antibiotic → yeast cycle
  • What Users Report:
  • Days 1-7: Initial support begins. Digestive comfort improves.
  • Days 8-30: pH balance support. Less bloating.
  • Days 60-90: Sustained ecosystem support. Increased confidence.
Get PuraBiome

Mobilize

Support Hormonal Joint Health

Common Struggles:

  • Hips that feel unstable during daily activities
  • Morning stiffness that takes time to ease
  • Movement limitations affecting quality of life
  • Discomfort interfering with sleep
  • What Users Report:
  • Week 1: Morning stiffness begins to ease.
  • Week 3: Improved mobility during daily activities.
  • Week 6-8: Better sleep. Side-sleeping more comfortable.
  • Week 12: Sustained joint comfort support.
Get Mobilize

Pleasure

Support for Intimate Vitality

Common Struggles:

  • Decreased interest in physical intimacy
  • Reduced sensation and responsiveness
  • Dryness and discomfort concerns
  • Loss of spontaneity in relationships
  • What Users Report:
  • Week 1-2: Subtle changes in awareness and comfort.
  • Week 3-4: Improved responsiveness and interest.
  • Week 6-8: More natural, spontaneous connection.

Why We're Different

eco

We Identify the Mechanism, finding the deep root cause

science

We Dose Clinically with all formula use research-backed levels

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We Target Systems (using our customers report to ungrade the quality)

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We Validate Your Reality - "It's not you, it's your hormones."

See The Combinations
local_offer Most supplements mask symptoms. We support root cause mechanisms.
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Bonnie , Clara and 12,000+ others love our products!

12,000 Women Trust Rejuvenate

Excellent 4.7 / 5

Based on 3446 verified reviews

Metabolize™

"I thought I was losing my mind. The brain fog was so bad I forgot my neighbor's name—someone I've known for 10 years. I'd walk into a room and have no idea why I was there. By 2 PM every day, I couldn't form complete sentences. My doctor tested me for thyroid issues, early-onset memory problems... nothing came back abnormal. Three weeks on METABOLIZE and it's like someone wiped the dirty windshield off my brain. I'm sharp again. I can think clearly. I'm ME again."

Metabolize™

"My jeans fit for the first time in 5 years. I've been stuck at 168 lbs since menopause started. It didn't matter if I ate 1,200 calories or 2,000—the scale wouldn't budge. The meno-belly just kept inflating like a balloon. Six weeks on METABOLIZE and I'm down to 154. But it's not just the number on the scale—my belly is actually FLAT again. I can zip my favorite jeans without lying down on the bed first. I actually cried in the dressing room yesterday. Happy tears."

Metabolize™

"My husband asked if I was taking something. The 2 PM crash used to hit me like a freight train. Brain fog so thick I'd forget what I was typing mid-sentence. I was taking 2-hour 'power naps' just to function. Now? I'm crushing work presentations at 4 PM and still have energy to hit the gym after. My husband literally asked, 'Are you on something?' YES—METABOLIZE. It's not caffeine jitters. It's sustained, clean energy. I feel 35 again."

PuraBiome™

"I have tried countless probiotics over the years, but nothing comes close to Pura-Biome. Within **one month**, I noticed a significant difference in my body's odor and balance. The combination of Ashwagandha and clinical Lactobacillus strains is a real powerhouse and combats my recurring infections like nothing else I've tried. I haven't taken Metronidazole in **5 months**. My gut feels calmer, my vagina feels CLEAN, and I finally feel confident in my own skin!"

PuraBiome™

"I've always struggled with recurring BV, especially the humiliating odor and discharge. I was hesitant to try Pura-Biome at first, but after using it for just **3 weeks**, I am blown away by the results! The fishy smell is GONE, and my discharge is finally normal and clear. My bloating disappeared too — I no longer look 6-months pregnant by evening. I'm really grateful for this product!"

Metabolize™

"I used to look pregnant after meals. 3 weeks on Metabolize and my stomach stays flat. So grateful for this formula!"

Mobilize 

"My hip discomfort improved significantly within days—after 2 years of trying everything. I didn't expect it to work this well."

Research-Backed Ingredients

  • 39x
    More absorbable curcumin formulation compared to standard turmeric
  • 28%
    Average cortisol reduction in clinical studies with KSM-66 Ashwagandha
  • 84%
    User satisfaction when supporting both gut + vaginal systems together
  • 12B
    CFU spore-based probiotics designed to survive stomach acid

Everything You Need To Know

How long until I notice changes?

Most women report noticing initial changes within 2-3 weeks, though individual results vary:

  • PuraBiome: Digestive comfort often improves in 7-14 days
  • Metabolize: Energy may stabilize in week 1, with metabolic changes emerging week 3-4
  • Mobilize: Morning stiffness may ease in week 1, with sustained comfort by week 3-6
  • Pleasure G: Subtle awareness changes in week 2, with more noticeable support by week 4-8

Full benefits typically develop over 60-90 days as your body adjusts and systems balance. Results vary based on individual health status, lifestyle, and consistency of use.

Can I take these with my current medications?

These are dietary supplements with natural ingredients. However, some ingredients may interact with certain medications:

  • Berberine (in Metabolize) may affect blood sugar levels—consult your doctor if you're taking diabetes medications
  • Ashwagandha (in PuraBiome) may interact with thyroid medications or immunosuppressants
  • Curcumin (in Mobilize) may have blood-thinning properties

Always inform your healthcare provider about all supplements you're taking, especially if you're on prescription medications, pregnant, nursing, or have a medical condition.

What if it doesn't work for me?

90-Day Empty Bottle Guarantee.Try the product for a full 90 days. If you don't experience meaningful improvement or aren't satisfied for any reason, contact us for a full refund—no questions asked. You don't even need to return the bottles. We believe in our formulas and want you to feel confident trying them risk-free.

How do I know these are safe?

Safety and quality are our top priorities:

  • Manufactured in FDA-registered, GMP-certified facilities in the USA
  • Third-party tested for purity, potency, and contaminants
  • Made with clinically-studied, research-backed ingredients
  • Free from artificial colors, preservatives, and common allergens
  • Each batch undergoes rigorous quality control testing

However, supplements are not evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any new supplement regimen.

Do I need to take all 4 products?

No—start with your primary concern. However, hormonal systems are interconnected. Many customers find that supporting multiple systems (e.g., gut + metabolism or joint + intimacy) provides more comprehensive benefits. Women who support multiple systems report 84% satisfaction vs. 65% when addressing one system alone. Our quiz can help you identify which combination is right for you.

What's the best way to take these supplements?

For optimal results:

  • Metabolize: Take 2 capsules once daily with a meal, preferably breakfast or lunch
  • PuraBiome: Take 2 capsules daily with food for best absorption
  • Mobilize: Take as directed with food to minimize any stomach sensitivity
  • Pleasure G: Take consistently at the same time each day for cumulative benefits

Consistency is key—try to take your supplements at the same time daily. If you miss a dose, simply continue with your regular schedule the next day.

Are these suitable for vegetarians/vegans?

Our formulas use vegetable cellulose capsules and are suitable for vegetarians. However, some products may contain ingredients derived from non-vegan sources (such as certain probiotic strains or processing agents). Check the specific product page for detailed ingredient information, or contact our customer support team for clarification about specific dietary requirements.

Will these cause any side effects?

Most women tolerate our formulas well. However, some may experience mild, temporary effects as the body adjusts:

  • Digestive changes: Mild bloating or changes in bowel movements (typically resolve within 3-5 days)
  • Berberine: May cause temporary stomach discomfort—taking with food helps
  • Probiotics: Brief adjustment period as gut flora balances

These effects are usually temporary and mild. If you experience persistent discomfort or adverse reactions, discontinue use and consult your healthcare provider.

How do subscriptions work? Can I cancel anytime?

Subscriptions provide convenience and savings (save 20% + free shipping). Here's how they work:

  • Choose your delivery frequency (30, 60, or 90 days)
  • Automatic refills arrive before you run out
  • Cancel, pause, or modify anytime from your account dashboard
  • No commitment, no cancellation fees, no hassle
  • Email reminders before each shipment

You're always in control. Many customers prefer subscriptions for the convenience and guaranteed savings, but one-time purchases are always available.

Do these products contain hormones or estrogen?

No. Our formulas do not contain synthetic hormones, estrogen, or hormone replacement therapy (HRT) compounds. Instead, we use:

  • Phytoestrogens: Plant compounds (like those in curcumin) that may support healthy hormonal balance naturally†
  • Adaptogens: Herbs like Ashwagandha that support the body's stress response†
  • Nutritional cofactors: Vitamins and minerals that support natural hormone production pathways†

Our approach supports your body's natural processes rather than introducing external hormones. Always consult your doctor if you're considering hormone therapy.

Not Sure Where to Start?

Take our 60-second assessment. We'll recommend the protocol that matches your primary concerns.

Join 12,000+ women who found their solution

Take the Assessment

What Our Community Is Saying

★★★★★
4.9 out of 5
Based on 11,032+ Verified Reviews
5 Stars
 
9.8k
4 Stars
 
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2 Stars
 
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Customer photos & videos
TRUSTED 10k+
Sort by: Most Helpful
★★★★★
12/08/2025
I thought I was losing my mind

The brain fog was so bad I forgot my neighbor's name—someone I've known for 10 years. My doctor tested me for everything and said I was fine. Three weeks on METABOLIZE and it's like someone wiped the dirty windshield off my brain. I'm ME again.

★★★★★
12/05/2025
I got my stride back (literally)

My doctor said it was "just age" and wanted me to take basic painkillers. He was wrong. Within 3 weeks of taking Mobilize, that awful "bone-on-bone" grinding feeling in my hips stopped. I walked 3 miles yesterday!

★★★★★
12/05/2025
Finally, no more balloon belly

I used to look 6 months pregnant after every meal. It didn't matter what I ate—salad, bread, anything set me off. 3 weeks on this and my stomach is actually flat by the end of the day. Crying happy tears!

★★★★★
12/04/2025
Didn't realize it was my hormones

I never connected my stiff knees to perimenopause until I read about "hormonal joints." I was taking glucosamine for years with zero results. This formula is different. The brain fog lifted first, then the joint pain vanished.

★★★★★
12/03/2025
I can walk past donuts now

The sugar cravings used to control my entire life. I'd "be good" all day, then at 9 PM I'd demolish a pint of ice cream standing at the freezer in shame. Week 2 on METABOLIZE, the cravings just... stopped. Like someone flipped a switch in my brain.

★★★★★
12/02/2025
Husband asked if I was taking something

The 2 PM crash used to hit me like a freight train. Now? I'm crushing work presentations at 4 PM and still have energy to hit the gym after.

★★★★★
12/01/2025
Skeptical but sold

I thought 'probiotics for down there?' sounded fake. I was wrong. It works. My jeans zip up easier and I feel cleaner.

★★★★★
11/29/2025
Gardening is fun again

I thought I'd have to give up my garden this year because I couldn't kneel or squat. 30 days on the Tendon Rejuvenation Protocol and I'm back in the dirt. No swelling the next day.

★★★★★
11/28/2025
The scale is finally moving DOWN

I did everything right. Tracked every calorie. Fasted cardio at 5:30 AM. And every single week, the scale went UP. METABOLIZE proved them all wrong. Down 11 lbs in 8 weeks.

★★★★★
11/27/2025
My rings fit again

I was so puffy I couldn't get my wedding ring off for 6 months. Four days on METABOLIZE and the water weight just... flushed out. My rings slide on easily now.

★★★★☆
11/26/2025
It works, but give it time

Shipping took a day longer than expected. But the product? Genuine relief. It didn't happen overnight, took about 10 days, but suddenly I realized I wasn't reaching for the railing when going downstairs.

★★★★★
11/25/2025
Impressed by the formulation

As a retired PT, I'm picky. Most joint supplements are junk fillers. The dosage of Boron and Green Lipped Mussel here is actually clinical strength. It lubricates the synovial fluid noticeably.

★★★★★
11/24/2025
The "food noise" finally shut up

There was a constant voice in my head: "Eat. You need sugar." Two weeks on METABOLIZE and the voice is just... gone. Silent. I can focus on work, on conversations, on LIFE.

★★★★★
11/23/2025
My doctor checked my numbers twice

My fasting glucose was creeping up—98, then 102. Three months on METABOLIZE and my latest test came back at 87. She literally asked me to repeat the test because she didn't believe it.

★★★★★
11/22/2025
Two birds, one stone

I bought this for my aching hips, but I stayed for the energy boost. The B12 in here is no joke. I don't need my afternoon coffee anymore, and I can actually go for a walk after work without feeling stiff.

★★★★★
11/21/2025
I fit into my "goal jeans" today

I kept a pair of jeans from 2018 in my closet as motivation. They have been taunting me for YEARS. This morning, I pulled them out as a joke—and they FIT. Not tight. Not uncomfortable. I cried.

★★★★★
11/20/2025
No more 3 PM zombie mode

Every single day at 3 PM, I would hit a wall. METABOLIZE fixed this in 2 weeks. My energy is FLAT all day long. No spikes, no crashes. Just steady, reliable fuel.

★★★★★
11/19/2025
My co-workers keep asking

Three people this week asked, 'Did you lose weight? You look amazing!' It's only been 5 weeks but the change is VISIBLE. My face is slimmer and I have this glow.

★★★★★
11/18/2025
I'm not "hangry" anymore

My family used to walk on eggshells around me before meals. METABOLIZE stabilized everything. I don't get that desperate, clawing hunger anymore. I'm calm. I'm pleasant.

★★★★★
11/17/2025
Tingling in fingers stopped

I had this weird tingling in my fingertips and toes for months. My doctor said it was probably nerve damage from high glucose. Five weeks on METABOLIZE and the tingling is GONE.

★★★★★
11/16/2025
Finally breaking the plateau

I was stuck at 172 lbs for 18 MONTHS. No matter what I tried—Keto, intermittent fasting, cutting carbs—the scale refused to move. METABOLIZE broke through in 4 weeks. I'm at 164 now.

★★★★★
11/15/2025
Stairs aren't scary anymore

We live in a two-story house and I was dreading the stairs. My knees would burn. Mobilize lubricated the joints within a week. I'm gliding up them now.

★★★★★
11/14/2025
Stopped the hip popping

Every time I stood up, my hip popped. It was embarrassing and painful. The "Tendon Rejuvenation" claim is real. Everything feels tighter and supported.

★★★★☆
11/13/2025
Better than turmeric

I tried high dose turmeric which helped inflammation but didn't help the "dry" feeling in my joints. This actually feels like it oiled the gears.

★★★★★
11/12/2025
Sleeping soundly

Pain kept me up at night. Since starting this, I sleep through. Reclaiming my independence starts with a good night's sleep!

★★★★★
11/11/2025
Wish I found this sooner

I wasted so much money on creams. This treats it from the inside. My fingers are less stiff in the morning too, which helps with my knitting.

★★★★★
11/10/2025
Brain fog is GONE

I was skeptical about the "energy matrix" part. But honestly? I feel 10 years younger mentally. The joint relief is just the cherry on top.

★★★★★
11/09/2025
Yoga is possible again

My downward dog was suffering because of wrist and shoulder pain. 6 weeks on this protocol and I'm back to my full practice.

★★★★★
11/08/2025
Grandkids can't keep up

I was sitting on the sidelines watching them play because getting up from the floor was a production. Now I'm on the floor building legos with them. Priceless.

★★★★★
11/07/2025
Smooth movement

It really does feel like someone oiled the joints. No more creaking sounds when I walk up the stairs.

★★★★☆
11/06/2025
Good product

Took about 3 weeks to kick in so be patient. But once it does, the difference is night and day.

★★★★★
11/05/2025
Confidence restored

I was always self-conscious about odor. Pura Biome fixed the internal pH balance. I feel fresh all day.

★★★★★
11/04/2025
Midsection shrinking

Menopause hit my waistline hard. Metabolize is the only thing that has targeted that stubborn belly fat.

★★★★★
11/03/2025
No more bloating

I can eat pizza again! Well, occasionally. But when I do, I don't look 6 months pregnant afterwards.

★★★★★
11/02/2025
Energy is through the roof

I cleaned my whole house on a Saturday. That hasn't happened in years. The energy is clean, not jittery.

★★★★★
11/01/2025
Shoulder pain gone

I couldn't lift my arm above my head to dry my hair. Now I have full range of motion.

★★★★★
10/31/2025
Life saver

If you suffer from recurring feminine issues, try this. It targets the root cause in the gut.

★★★★☆
10/30/2025
It works

Down 5 pounds in the first month. Slow and steady wins the race.

★★★★★
10/29/2025
Knees feel 20 again

I can squat down to pick things up without making "the noise". Highly recommend.

★★★★★
10/28/2025
Regularity

I am finally regular. My digestion is smooth and I feel so much lighter.

★★★★★
10/27/2025
Glucose support

My doctor is very happy with my recent bloodwork. This was the only change I made.

★★★★★
10/26/2025
Tennis elbow relief

I thought I'd have to stop playing tennis. Mobilize helped the tendons heal faster.

★★★★★
10/25/2025
Wonderful

It really helps with the bloating.

★★★★★
10/24/2025
More energy

I don't need a nap in the afternoon anymore.

★★★★★
10/23/2025
Pain free

My knuckles don't hurt when I type.

★★★★★
10/22/2025
Gut health

Everything is just moving better.

★★★★★
10/21/2025
Finally losing weight

It is slow but it is happening!

★★★★★
10/20/2025
Great for back pain

My lower back is much less stiff in the mornings.

★★★★★
10/19/2025
Happy customer

Will be buying again.

★★★★★
10/18/2025
Cravings gone

I don't even look at the candy aisle anymore.

★★★★★
10/17/2025
It helps

I can walk further without pain.

★★★★★
10/16/2025
Great product

Highly recommended for women's health.